Membrane Research: Classic Origins and Current Concepts is a special volume of the International Review of Cytology dedicated to Dr. Danielli on the occasion of his retirement from official duties. The central theme of the volume is membranes. The diversity of topics ranges from the biogenesis of membranes and their components, to the use of optical and lectin probes as a means to study the structure, physiology, and interactions of cell components and organelles in plant and animal systems. The book begins with a study on the cell surface of the mammalian embryo and the events associated with the formation of the differentiated blastocyst. This is followed by separate chapters on the structural associations between the inner and outer bacterial membrane; the interactions of cell wall and membrane in plant cells; the morphological and functional aspects of membranes; and methods for studying the physiology of cell and organelles at the membrane level. Subsequent chapters deal with the synthesis of cellular proteins and glycoproteins; techniques for fixing and preserving the ultrastructure of the membrane; the synthesis of artificial organelles; and the effects of drugs and chemicals on membrane transport utilizing kidney tissue and vesicles. This book provides an outstanding reference source for all scientific researchers and teachers.