Advances in Biology of Skin, Vol. I: Cutaneous Innervation focuses on the biology of skin, including the chemistry of the ground substance of the dermis to the biology of sebaceous glands. The selection first offers information on the pattern of cutaneous innervation of the human hand, foot, and breast and similarities in cutaneous nerve end-organs. Discussions focus on the methods of study, observations, histochemical reactions, and function of end-organs. The text then examines the autonomic innervation of the skin, cholinesterases in the cutaneous nerves of man, and the relation of nerve fiber size to modality of sensation. The manuscript ponders on the central paths of the afferent impulses from skin that arouse sensation and studies related to the mechanism of common sensibility, including materials and methods, anatomical and physiological observations, and interpretation of observations. The publication also takes a look at the structures and processes involved in the sensation of itch and the pathophysiology of itch sensation. The selection is a dependable reference for readers interested in the biology of skin.